29 06, 2020

SEVERE AND PROGRESSIVE NEURONAL LOSS IN MYELOMENINGOCELE BEGINS BEFORE 16 WEEKS OF PREGNANCY

Par |2020-06-29T10:39:35+01:0029 juin, 2020|Catégories : CHIRURGIE FOETALE|Mots-clés : , , |Commentaires fermés sur SEVERE AND PROGRESSIVE NEURONAL LOSS IN MYELOMENINGOCELE BEGINS BEFORE 16 WEEKS OF PREGNANCY


Selima Ben Miled MD a, b, e, Laurence Loeuillet MD b, Jean-Paul Duong Van Huyen MD, PhD c, Bettina Bessières MD b, Amel Sekour MS b, Brigitte Leroy MD f, Julia Tantau MD f, Homa Adle-Biassette MD, PhD g, Houria Salhi MD b, Maryse Bonnière-Darcy MD b, Aude Tessier MD b, Jelena Martinovic MD b, Frédéric Causeret PhD h, Julie Bruneau MD, PhD c, Yoann Saillour PhD h, Syril James MD d, Yves Ville MD, PhD a, e, Tania Attie-Bitach MD, PhD b, i, Ferechte Encha-Razavi MD b, Julien Stirnemann MD, PhD a, e

a Department of Obstetrics and Maternal-Fetal Medicine, Necker-Enfants Malades Hospital, AP-HP and Paris Descartes University

b Department of Histology-Embryology and Cytogenetics, Unit of Embryo & Fetal Pathology, Necker-Enfants

Malades Hospital, AP-HP and Paris Descartes University

c Department of Pathology, Necker-Enfants Malades Hospital, AP-HP and Paris Descartes University

d Department of Pediatric Neurosurgery, Necker-Enfants Malades Hospital, AP-HP and Paris Descartes University

e EHU FETUS, Université de Paris and IMAGINE Institute

f Department of Pathology, Poissy Saint Germain-en-Laye Hospital, Versailles Saint-Quentin-en-Yvelines University

g Department of Neuropathology, Lariboisière Hospital, AP-HP and Paris Diderot University

h Institute of Psychiatry and Neuroscience of Paris, INSERM U1266, & IMAGINE Institute

i INSERM UMR 1163, IMAGINE Institute

(suite…)

31 01, 2019

SUCCESSFUL IN UTERO TRANSESOPHAGEAL PACING FOR SEVERE DRUG-RESISTANT TACHYARRHYTHMIA

Par |2019-08-31T10:40:07+01:0031 janvier, 2019|Catégories : CHIRURGIE FOETALE|Mots-clés : , , |0 commentaire

Successful in utero transesophageal pacing for severe drug-resistant tachyarrhythmia
Stirnemann, Julien et al.
American Journal of Obstetrics & Gynecology , Volume 219 , Issue 4 , 320 – 325

Sustained fetal tachyarrhythmia can evolve into a life-threatening condition in 40% of cases when hydrops develops, with a 27% risk of perinatal death. Several antiarrhythmic drugs can be given solely or in combination to the mother to achieve therapeutic transplacental concentrations. Therapeutic failure could lead to progressive cardiac insufficiency and restrict therapeutic options to either elective delivery or direct fetal administration of antiarrhythmic drugs, which may increase the risk of death. We report for the first time successful fetal transesophageal pacing to treat a hydropic fetus with drug-resistant tachyarrhythmia.