août 2018 - PACT-NECKER

PRETERM PREMATURE RUPTURE OF MEMBRANES IS A COLLATERAL EFFECT OF IMPROVEMENT IN PERINATAL OUTCOMES FOLLOWING FETOSCOPIC COAGULATION OF CHORIONIC VESSELS FOR TWIN-TWIN TRANSFUSION SYNDROME: A RETROSPECTIVE OBSERVATIONAL STUDY OF 1092 CASES

Par Administrateur|2018-09-01T09:48:47+01:0031 août, 2018|Catégories : CHIRURGIE FOETALE|Mots-clés : FETOSCOPIC COAGULATION, FŒTOSCOPIE, STT, TTTS|0 commentaire

Preterm premature rupture of membranes is a collateral effect of improvement in perinatal outcomes following fetoscopic coagulation of chorionic vessels for twin-twin transfusion syndrome: a retrospective observational study of 1092 cases

J Stirnemann, F Djaafri, A Kim, Mediouni, L Bussieres, E Spaggiari, C Veluppillai, A Lapillonne, E Kermorvant, J·F Magny, C Colmant, Y Ville

BJOG https://doi.org/10.1111/1471-0528.15147

Preterm premature rupture of membranes (PPROM) is a leading complication following fetoscop ic laser coagulation (FLC) for twin-twi n transfusion syndrome (TTTS). Our primary objective was to describe the impact of improvements in surgical technique on survival and rate of PPROM over time .. The secondary objective was to assess potential risk factors for PPROM.

EFFECT OF CELL-FREE DNA SCREENING VS DIRECT INVASIVE DIAGNOSIS ON MISCARRIAGE RATES IN WOMEN WITH PREGNANCIES AT HIGH RISK OF TRISOMY 21. A RANDOMIZED CLINICAL TRIAL

Effect of Cell-Free DNA Screening vs Direct Invasive Diagnosis on Miscarriage Rates in Women With Pregnancies at High Risk of Trisomy 21. A Randomized Clinical Trial

Valérie Malan, MD, PhD; Laurence Bussières, PhD; Norbert Winer, MD, PhD; et al

JAMA. 2018;320(6):557 565. doi:10.1001/jama.2018.9396

Question: Does performing cell-free DNA testing on women with pregnancies at high risk of trisomy 21, followed by invasive testing only if cell-free DNA test results are positive, reduce the rate of miscarriage compared with immédiate invasive testing?